Behavioral teratology of ethylene glycol monomethyl and monoethyl ethers.

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Behavioral teratology of ethylene glycol monomethyl and monoethyl ethers.

A recent addition to the field of teratology has been the inclusion of functional assessment techniques of offspring after prenatal exposure to exogenous agents. The present paper reviews the behavioral teratogenic effects of ethylene glycol monomethyl ether (EGME, 2-methoxyethanol) and ethylene glycol monoethyl ether (EGEE, 2-ethoxyethanol). Groups of 15 pregnant Sprague-Dawley rats were expos...

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Ethylene glycol monoethyl ether and ethylene glycol monoethyl ether acetate teratology studies.

An inhalation teratology study was conducted in rats at 10, 50 and 250 ppm ethylene glycol monoethyl ether (EGEE) and in rabbits at 10, 50 and 175 ppm EGEE. This study was designed to supplement a study conducted for NIOSH which showed teratogenic effects in rats at 200 ppm EGEE and in rabbits at about 160 ppm EE. In this study, EGEE was found not to cause teratogenic effects at concentrations ...

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Testicular toxicity produced by ethylene glycol monomethyl and monoethyl ethers in the rat.

Ethylene glycol monomethyl ether (EGME) and ethylene glycol monoethyl ether (EGEE) were administered orally to young male rats at doses varying from 50 to 500 mg/kg/day and 250 to 1000 mg/kg/day for EGME and EGEE, respectively, for 11 days. At sequential times animals were killed and testicular histology examined. The initial and major site of damage following EGME treatment was restricted to t...

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Evaluation of workers exposed to ethylene glycol monomethyl ether and ethylene glycol monomethyl ether acetate.

OBJECTIVES Ethylene glycol monomethyl ether (EGME) and ethylene glycol monomethyl ether acetate (EGMEA) are widely used in industries as solvents for coatings, paint and ink, but exposure data are limited because they are minor components out of mixed solvents, as well as because of inconsistency in desorption solvent use. The objective of this study was to investigate the worker exposure profi...

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Criteria Document for Swedish Occupational Standards. Ethylene glycol monomethyl ether and ethylene glycol monomethyl ether acetate

The labour market, occupational safety and health, and work organisation are our main fields of activity. The creation and use of knowledge through learning, information and documentation are important to the Institute, as is international cooperation. The Institute is collaborating with interested parties in various development projects. The areas in which the Institute is active include: • la...

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ژورنال

عنوان ژورنال: Environmental Health Perspectives

سال: 1984

ISSN: 0091-6765,1552-9924

DOI: 10.1289/ehp.845743